BackgroundThe COVID-19 vaccination campaign in the US has been immensely successful in vaccinating those who are receptive, further increases in vaccination rates however will require more innovative approaches to reach those who remain hesitant.Developing vaccination strategies that are modelled on what people want could further increase uptake.Me

Understanding the mechanisms that protect against or limit muscle atrophy in hibernators during prolonged inactivity has important implications for its treatment.We examined whether external factors influence the pathways regulating protein synthesis and degradation, leading to muscle atrophy prevention in Daurian ground squirrels (Spermophilus dau

Abstract Tri-level optimization problems are optimization problems with three nested hierarchical structures, where in most cases conflicting objectives are set at each level of NUTRI B12 hierarchy.Such problems are common in management, engineering designs and in decision making situations in general, and are known to be strongly NP-hard.Existing

Sarra Sebaa,1,2 Maxime Faltot,1 Sandra De Breucker,3 Zahia Boucherit-Otmani,2 Françoise Bafort,4 Jean-Paul Perraudin,5 Philippe Courtois1 1Laboratory of Physiology and Pharmacology, Université Libre de Bruxelles, Brussels, Belgium; 2Laboratory of Antibiotics and Antifungals: Physico-Chemistry, Synthesis and Biological Activity, Univer

Exercise is a treatment paradigm that can ameliorate cognitive dysfunction in Alzheimer disease (AD) and AD mouse models.Since exercise is also known to alter the peripheral immune response, one potential mechanism for the cognitive improvement following exercise may be by modulating the inflammatory repertoire in the central VERVAIN nervous system